​​Identify actionable mutations in East Asian cancer patients with COSMIC 56min 34 sec

Speakers

Simon Forbes, PhD, Head of COSMIC, Wellcome Sanger Institute

Zbyslaw Sondka, PhD, Head of Science, COSMIC, Wellcome Sanger Institute

Who should attend?

Cancer scientists and clinical developers (pharmaceutical, diagnostic, academic), bioinformatic scientists, developers & solution providers.

Summary

What to expect?

• Introduction to COSMIC & its hand-curated content
• Every gene has a pattern of somatic mutations in cancer, we describe over 700 pathogenic genes in functional detail in the Cancer Gene census
• Phenotypic & genotypic annotations are described at high resolution, inaccessible and integrable formats
• We describe mutations which also drive resistance to precision medications
• Mutations which drive cancer cover many genetic mechanisms, all described in COSMIC
• What’s new? The Cancer Mutation Census details metrics for every mutation to measure its impact in disease, Mutation Actionability - which mutations are druggable (and how successful are they?)
• How to identify driving and actionable mutations present in East Asian cancer patients?
• How to download? - everything in easy-to use datasheets for private analysis and integration