How to access COSMIC data

Let data uncover key insights to support your research

COSMIC data is available in multiple formats

We understand that different users have different requirements and bioinformatics capabilities. Therefore, we provide a format to suit every type of use case. 

Over the last 21 years, we have developed a web platform and data downloads, which we update twice a year with the latest variants included in each COSMIC release.

Which format will best meet your needs?

Our web platform for effortless navigation and powerful insights

Need effortless navigation and powerful insights?

Explore COSMIC’s extensive Knowledgebase by searching for a specific cancer, gene, or mutation. 

Our intuitive web tool is designed to connect you to key associations and supporting evidence and help you uncover critical insights. 

Advanced search functions and genome browsers guide you to precise genomic positions linked to cancer mutations to streamline your discovery and analysis.

Are you a registered COSMIC account holder?

For registered account holders, our website search browser provides rapid insights.

Why use the web platform?

  • Quick and intuitive: Ready to use, no setup required.
  • Up-to-date data: Instant access to the latest COSMIC release.
  • Interactive filtering: Refine your searches in real-time.

Watch this short video to see how COSMIC helps you:

  • Explore cancers of interest
  • Uncover key genes
  • Gain critical insights to power your research

Need flexible access and interoperability? 

You can download COSMIC data and integrate it into various tools, including bioinformatics pipelines and oncology research software.

COSMIC data is available in structured flat files, with an accompanying ReadMe file, allowing you to select the most relevant datasets for your needs. 

Unique IDs ensure interoperability across files and releases, enabling seamless integration and analysis. 

To keep research at the forefront and deliver the latest insights in cancer genomics, we update Core COSMIC data twice a year.

Why use data download?

  • Full dataset access: Ideal for large-scale analysis.
  • Offline analysis: No need for an active internet connection.
  • Customisable: Integrate data into proprietary tools and specific workflows.
An aerial photo of the Wellcome Genome Campus

Add context to your sequencing data

Click the link below to register and access COSMIC